A cell-permeable fluorescent potassium indicator
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IPG-2 AM

Item No. 35540

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-[(acetyloxy)methoxy]-4,5-dichloro-9-[3-methoxy-4-[16-(2-methoxy-4-methylphenyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]phenyl]-3-oxo-3H-xanthene-2,7-dipropanoic acid, 2,7-bis[(acetyloxy)methyl] ester
CAS Number
1369302-24-8
Synonyms
  • APG-2 Acetoxymethyl ester
  • APG-2 AM
  • Asante Potassium Green-2 Acetoxymethyl ester
  • Asante Potassium Green-2 AM
  • ION Potassium Green-2 Acetoxymethyl ester
  • ION Potassium Green-2 AM
  • IPG-2 Acetoxymethyl ester
Molecular Formula
C55H64Cl2N2O19
Formula Weight
1128.0
Purity
≥90%
Emission
545 nm
Excitation
525 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
O=C(C)OCOC(CCC1=CC2=C(C3=CC(OC)=C(N4CCOCCOCCN(CCOCCOCC4)C5=C(OC)C=C(C)C=C5)C=C3)C6=CC(CCC(OCOC(C)=O)=O)=C(OCOC(C)=O)C(Cl)=C6OC2=C(C1=O)Cl)=O
InChi Code
InChI=1S/C55H64Cl2N2O19/c1-34-7-11-43(45(27-34)66-5)58-15-19-68-23-25-70-21-17-59(18-22-71-26-24-69-20-16-58)44-12-8-38(30-46(44)67-6)49-41-28-39(9-13-47(63)75-31-72-35(2)60)52(65)50(56)54(41)78-55-42(49)29-40(10-14-48(64)76-32-73-36(3)61)53(51(55)57)77-33-74-37(4)62/h7-8,11-12,27-30H,9-10,13-26,31-33H2,1-6H3
InChi Key
FLNBWSAACUIXPZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 x 50 µg

    $478

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    500 µg

    $478

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    Product Description

    IPG-2 AM is a cell-permeable fluorescent potassium indicator. It binds to potassium (Kd = 18 mM) and displays excitation/emission maxima of 525/545 nm, respectively. IPG-2 AM has been used to kinetically monitor potassium levels in isolated human platelets via flow cytometry.1 IPG-2 is also available in a cell-impermeable form (Item No. 35533).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aliotta, A., Calderara, D.B., and Alberio, L. Flow cytometric monitoring of dynamic cytosolic calcium, sodium, and potassium fluxes following platelet activation. Cytometry A. 97(9), 933-944 (2020).