An acetylated form of L-isoleucine
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Isomer(s)
30489N-acetyl-D-Leucine
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N-acetyl-L-Isoleucine

Item No. 35545

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
3077-46-1
Synonyms
  • N-Acetylisoleucine
  • NSC 203807
Molecular Formula
C8H15NO3
Formula Weight
173.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 14 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
CC[C@H](C)[C@H](NC(C)=O)C(O)=O
InChi Code
InChI=1S/C8H15NO3/c1-4-5(2)7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t5-,7-/m0/s1
InChi Key
JDTWZSUNGHMMJM-FSPLSTOPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 g

    $57

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    100 g

    $91

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    250 g

    $209

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    500 g

    $390

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    Product Description

    N-acetyl-L-Isoleucine is an acetylated form of L-isoleucine. Urine levels of N-acetyl-L-isoleucine are increased in patients with maple syrup urine disease (MSUD), an inborn error of metabolism characterized by a deficiency in the branched-chain α-ketoacid dehydrogenase complex, the complex that catalyzes the degradation of branched-chain amino acids, leading to the accumulation of branched-chain amino acids in the plasma and urine, a maple syrup-like odor in the urine, and neurological impairments.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jellum, E., Horn, L., Thoresen, O., et al. Urinary excretion of N-acetyl amino acids in patients with some inborn errors of amino acid metabolism. Scand. J. Clin. Lab. Invest. Suppl. 184, 21-26 (1986).