An amino acid
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N-Formylmethionine

Item No. 35594

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-formyl-L-methionine
CAS Number
4289-98-9
Synonyms
  • NSC 334322
Molecular Formula
C6H11NO3S
Formula Weight
177.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mLDMSO: 12 mg/mLEthanol: 2 mg/mLPBS (pH 7.2): 5 mg/mL
SMILES
OC([C@@H](NC=O)CCSC)=O
InChi Code
InChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChi Key
PYUSHNKNPOHWEZ-YFKPBYRVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $29

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    500 mg

    $54

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    1 g

    $91

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    5 g

    $393

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    Product Description

    N-Formylmethionine is an amino acid encoded by AUG, the start codon for protein synthesis.1 It is the N-terminal amino acid in the majority of proteins in prokaryotic systems but is commonly removed post-translationally. Levels of N-formylmethionine are positively correlated with the incidence of renal disease, heart failure, coronary artery disease, abdominal aortic aneurysms, chronic obstructive pulmonary disease (COPD), as well as mortality.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pelley, J.W. Protein synthesis and degradation. Elsevier's Integrated Biochemistry 147-158 (2007).

    2. Cai, N., Gomez-Duran, A., Yonova-Doing, E., et al. Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases. Nat. Med. 27(9), 1564-1575 (2021).