A phosphorylated form of creatine
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Creatine Phosphate

Item No. 35598

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[imino(phosphonoamino)methyl]-N-methyl-glycine
CAS Number
67-07-2
Synonyms
  • Phosphocreatine
Molecular Formula
C4H10N3O5P
Formula Weight
211.1
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 3 mg/ml
SMILES
O=C(CN(C)C(NP(O)(O)=O)=N)O
InChi Code
InChI=1S/C4H10N3O5P/c1-7(2-3(8)9)4(5)6-13(10,11)12/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12)
InChi Key
DRBBFCLWYRJSJZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $51

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    5 g

    $215

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    10 g

    $380

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    Product Description

    Creatine phosphate is a phosphorylated form of creatine that is involved in energy storage in skeletal muscle and brain.1,2 It is formed from creatine by creatine kinase. Creatine phosphate (10 mM) reduces hydrogen peroxide- and ferrous ion-induced increases in malondialdehyde (MDA) levels in rat heart microsomes.3 It also prevents hydrogen peroxide-induced decreases in aortic flow, minute work, and peak aortic pressure in isolated perfused rat hearts when used at a concentration of 10 mM. Brain levels of creatine phosphate decrease following mild traumatic brain injury in rats.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wallimann, T., Wyss, M., Brdiczka, D., et al. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: The 'phosphocreatine circuit' for cellular energy homeostasis. Biochem. J. 281(Pt 1), 21-40 (1992).

    2. Wyss, M., and Kaddurah-Daouk, R. Creatine and creatinine metabolism. Physiol. Rev. 80(3), 1107-1213 (2000).

    3. Zucchi, R., Poddighe, R., Limbruno, U., et al. Protection of isolated rat heart from oxidative stress by exogenous creatine phosphate. J. Mol. Cell. Cardiol. 21(1), 67-73 (1989).

    4. Signoretti, S., Di Pietro, V., Vagnozzi, R., et al. Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat. Mol. Cell. Biochem. 333(1-2), 269-277 (2010).