A flavonoid with radical scavenging and enzyme inhibitory activities
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Camelliaside A

Item No. 35628

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[(O-6-deoxy-α-L-mannopyranosyl-(1→6)-O-[β-D-galactopyranosyl-(1→2)]-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number
135095-52-2
Molecular Formula
C33H40O20
Formula Weight
756.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
λmax
214, 263, 330 nm
SMILES
O=C(C(O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O)O)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)=C(C4=CC=C(C=C4)O)OC5=CC(O)=C6)C5=C6O
InChi Code
InChI=1S/C33H40O20/c1-10-19(38)23(42)26(45)31(48-10)47-9-17-21(40)25(44)30(53-32-27(46)24(43)20(39)16(8-34)50-32)33(51-17)52-29-22(41)18-14(37)6-13(36)7-15(18)49-28(29)11-2-4-12(35)5-3-11/h2-7,10,16-17,19-21,23-27,30-40,42-46H,8-9H2,1H3/t10-,16+,17+,19-,20-,21+,23+,24-,25-,26+,27+,30+,31+,32-,33-/m0/s1
InChi Key
VNLOLXSJMINBIS-XWAGUSETSA-N
Origin
Plant/Camellia oleifera
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $44

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    1 mg

    $84

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    5 mg

    $390

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    10 mg

    $605

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    Product Description

    Camelliaside A is a flavonoid that has been found in C. sinensis and has radical scavenging and enzyme inhibitory activities.1,2,3,4 It scavenges superoxide radicals in a cell-free assay (IC50 = 137.44 µM).1 Camelliaside A (1 µM) inhibits recombinant human monoamine oxidase B (MAO-B) in a cell-free assay.4 It also inhibits 5-lipoxygenase (5-LO) in RBL-1 rat basophilic leukemia cells (IC50 = 390 µM).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kang, B., Chang, H., Na, Y.J., et al. Extract of enzyme-hydrolyzed green tea seed as potent melanin synthesis inhibitor. Bull. Korean Chem. Soc. 34(7), 2199-2202 (2013).

    2. Park, J.S., Rho, H.S., Kim, D.H., et al. Enzymatic preparation of kaempferol from green tea seed and its antioxidant activity. J. Agric. Food Chem. 54(8), 2951-2956 (2006).

    3. Sekine, T., Arai, Y., Ikegami, F., et al. Isolation of camelliaside C from "tea seed cake" and inhibitory effects of its derivatives on arachidonate 5-lipoxygenase. Chem. Pharm. Bull. (Tokyo) 41(6), 1185-1187 (1993).

    4. Shkondrov, A., Krasteva, I., Bucar, F., et al. A new tetracyclic saponin from Astragalus glycyphyllos L. and its neuroprotective and hMAO-B inhibiting activity. Nat. Prod. Res. 34(4), 511-517 (2020).