An MOG antigen peptide
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MOG (35-55) (mouse, rat) (trifluoroacetate salt)

Item No. 35644

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-methionyl-L-α-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-seryl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl-L-lysine, trifluoroacetate salt
Synonyms
  • MEVGWYRSPFSRVVHLYRNGK
  • Myelin Oligodendrocyte Glycoprotein (35-55)
Molecular Formula
C118H177N35O29S • XCF3COOH
Formula Weight
2582.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: soluble
SMILES
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N4CCC[C@H]4C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC5=CNC=N5)C(N[C@H](C(N[C@@H](CC6=CC=C(O)C=C6)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CCCCN[H])C(O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N[H].OC(C(F)(F)F)=O
InChi Code
InChI=1S/C118H177N35O29S.C2HF3O2/c1-61(2)47-80(103(169)143-81(49-66-30-34-70(156)35-31-66)104(170)139-75(26-17-42-129-116(122)123)99(165)145-86(53-90(121)158)98(164)133-56-91(159)136-79(115(181)182)25-15-16-41-119)142-108(174)85(52-69-55-128-60-135-69)147-112(178)95(63(5)6)152-113(179)96(64(7)8)151-101(167)77(28-19-44-131-118(126)127)141-109(175)87(58-154)148-106(172)83(48-65-21-11-10-12-22-65)146-110(176)89-29-20-45-153(89)114(180)88(59-155)149-100(166)76(27-18-43-130-117(124)125)140-105(171)82(50-67-32-36-71(157)37-33-67)144-107(173)84(51-68-54-132-74-24-14-13-23-72(68)74)137-92(160)57-134-111(177)94(62(3)4)150-102(168)78(38-39-93(161)162)138-97(163)73(120)40-46-183-9;3-2(4,5)1(6)7/h10-14,21-24,30-37,54-55,60-64,73,75-89,94-96,132,154-157H,15-20,25-29,38-53,56-59,119-120H2,1-9H3,(H2,121,158)(H,128,135)(H,133,164)(H,134,177)(H,136,159)(H,137,160)(H,138,163)(H,139,170)(H,140,171)(H,141,175)(H,142,174)(H,143,169)(H,144,173)(H,145,165)(H,146,176)(H,147,178)(H,148,172)(H,149,166)(H,150,168)(H,151,167)(H,152,179)(H,161,162)(H,181,182)(H4,122,123,129)(H4,124,125,130)(H4,126,127,131);(H,6,7)/t73-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,94-,95-,96-;/m0./s1
InChi Key
BKNMIYVANFRKLG-OJAQWBQBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $82

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    1 mg

    $154

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    5 mg

    $482

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    10 mg

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    Product Description

    Myelin oligodendrocyte glycoprotein (MOG) (35-55) is an antigen peptide of MOG, a protein involved in demyelinating CNS disorders.1,2 MOG (35-55) in combination with heat-killed M. tuberculosis and complete Freund’s adjuvant (CFA) induces demyelination of the spinal cord, degeneration of the optic nerve, and visual impairments in mice.1 Immunization with MOG (35-55) in combination with adjuvants has been used to induce experimental autoimmune encephalomyelitis (EAE) in animal models of multiple sclerosis.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guo, X., Harada, C., Namekata, K., et al. Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice. PLoS One 5(9), e13083 (2010).

    2. Zhang, F., Wei, W., Chai, H., et al. Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration. J. Immunol. 190(3), 1017-1025 (2013).