A neuropeptide
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Kisspeptin-10 (zebrafish) (trifluoroacetate salt)

Item No. 35652

Technical Information
Formal Name
L-tyrosyl-L-asparaginyl-L-leucyl-L-asparaginyl-L-seryl-L-phenylalanylglycyl-L-leucyl-L-arginyl-L-tyrosinamide, trifluoroacetate salt
Synonyms
  • Kp-10
  • Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2
Molecular Formula
C58H84N16O15 • XCF3COOH
Formula Weight
Purity
≥98%
A solid
Peptide Sequence
YNLNSFGLRY-NH2
DMF: 10 mg/mlDMSO: 20 mg/ml
SMILES
OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C58H84N16O15.C2HF3O2/c1-30(2)21-40(53(85)68-38(11-8-20-65-58(63)64)52(84)69-39(49(62)81)24-34-14-18-36(77)19-15-34)67-48(80)28-66-51(83)42(25-32-9-6-5-7-10-32)72-57(89)45(29-75)74-56(88)44(27-47(61)79)73-54(86)41(22-31(3)4)71-55(87)43(26-46(60)78)70-50(82)37(59)23-33-12-16-35(76)17-13-33;3-2(4,5)1(6)7/h5-7,9-10,12-19,30-31,37-45,75-77H,8,11,20-29,59H2,1-4H3,(H2,60,78)(H2,61,79)(H2,62,81)(H,66,83)(H,67,80)(H,68,85)(H,69,84)(H,70,82)(H,71,87)(H,72,89)(H,73,86)(H,74,88)(H4,63,64,65);(H,6,7)/t37-,38-,39-,40-,41-,42-,43-,44-,45-;/m0./s1
InChi Key
NLKCQISWERNVDT-PKUMMGJCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Kisspeptin-10 is a neuropeptide expressed in zebrafish brains, ovaries, and testes and is involved in gonadal development and steroid expression.1 It increases levels of the mRNA encoding luteinizing hormone (Lh) receptor, as well as progestin receptor a (Pra) and Prb, in isolated zebrafish ovarian follicles when used at a concentration of 10 ng/ml. Kisspeptin-10 increases luteinizing hormone serum levels in female, but not male, goldfish when administered at doses of 0.1 and 1 µg/g.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hatef, A., Rajeswari, J.J., and Unniappan, S. Kisspeptin stimulates oocyte maturation, and food deprivation modulates the abundance of kisspeptin system in zebrafish gonads. Aquacult. Fish. 7(5), 484-493 (2022).

    2. Li, S., Zhang, Y., Liu, Y., et alStructural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus). J. Endocrinol. 201(3), 407-418 (2009).