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Item No. 35652

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Kisspeptin-10 is a neuropeptide expressed in zebrafish brains, ovaries, and testes and is involved in gonadal development and steroid expression.1 It increases levels of the mRNA encoding luteinizing hormone (Lh) receptor, as well as progestin receptor a (Pra) and Prb, in isolated zebrafish ovarian follicles when used at a concentration of 10 ng/ml. Kisspeptin-10 increases luteinizing hormone serum levels in female, but not male, goldfish when administered at doses of 0.1 and 1 µg/g.2
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1. Kisspeptin stimulates oocyte maturation, and food deprivation modulates the abundance of kisspeptin system in zebrafish gonads. Aquacult. Fish. 7(5), 484-493 (2022).
2. Structural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus). J. Endocrinol. 201(3), 407-418 (2009).