A lysophospholipid
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1-10(Z)-Heptadecenoyl-2-hydroxy-sn-glycero-3-PE

Item No. 35672

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
10z-heptadecenoic acid, (2R)-3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester
CAS Number
1246298-09-8
Synonyms
  • LPE(17:1)
  • 17:1 Lyso PE
  • PE(17:1/0:0)
Molecular Formula
C22H44NO7P
Formula Weight
465.6
Purity
≥98% (9:1 mixture of 1-acyl and 2-acyl)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
O=C(CCCCCCCC/C=C\CCCCCC)OC[C@@H](O)COP(OCCN)(O)=O
InChi Code
InChI=1S/C22H44NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23/h7-8,21,24H,2-6,9-20,23H2,1H3,(H,26,27)/b8-7-/t21-/m1/s1
InChi Key
RVPLNCFWJATBMI-GIWCCYDRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    1-10(Z)-Heptadecenoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid. Extracellular levels of 1-10(Z)-heptadecenoyl-2-hydroxy-sn-glycero-3-PE in M. tuberculosis culture supernatant increase in response to S. miltiorrhiza antibacterial tanshinones.1 It has been used as an internal standard for the quantification of lysophosphoethanolamines.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sieniawska, E., Sawicki, R., Marchev, A.S., et al. Tanshinones from Salvia miltiorrhiza inhibit Mycobacterium tuberculosis via disruption of the cell envelope surface and oxidative stress. Food Chem. Toxicol. 156, 112405 (2021).

    2. Medved, J., Knott, B.M., Tarrah, S.N., et al. The lysophospholipid-binding molecule CD1D is not required for the alloimmunization response to fresh or stored RBCs in mice despite RBC storage driving alterations in lysophospholipids. Transfusion 61(7), 2169-2178 (2021).

    3. Li, M., Feng, B., Liang, Y., et al. Lipid profiling of human plasma from peritoneal dialysis patients using an improved 2D (NP/RP) LC-QToF MS method. Anal. Bioanal. Chem. 405(21), 6629-6638 (2013).