A phenolic acid with antibacterial and anticancer activities
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Ginkgolic Acid C17:1

Item No. 35737

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(10Z)-10-heptadecen-1-yl-6-hydroxy-benzoic acid
CAS Number
111047-30-4
Synonyms
  • Ginkgolic Acid II
Molecular Formula
C24H38O3
Formula Weight
374.6
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
SMILES
OC1=CC=CC(CCCCCCCCC/C=C\CCCCCC)=C1C(O)=O
InChi Code
InChI=1S/C24H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21-19-17-20-22(25)23(21)24(26)27/h7-8,17,19-20,25H,2-6,9-16,18H2,1H3,(H,26,27)/b8-7-
InChi Key
MBYNDKVOZOAOIS-FPLPWBNLSA-N
Origin
Plant/Ginkgo biloba
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $70

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    5 mg

    $307

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    10 mg

    $544

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    Product Description

    Ginkgolic acid C17:1 is a phenolic acid that has been found in G. biloba with antibacterial and anticancer activities.1,2 It inhibits enterohemorrhagic E. coli O157:H7 (EHEC) biofilm formation when used at a concentration of 5 µg/ml.1 Ginkgolic acid C17:1 (50 µM) inhibits JAK2 phosphorylation and STAT3 activation in, and reduces the viability of, U266 cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, J.-H., Kim, Y.-G., Ryu, S.Y., et al. Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157:H7 and Staphylococcus aureus biofilm formation. Int. J. Food Microbiol. 174, 47-55 (2014).

    2. Baek, S.H., Lee, J.H., Kim, C., et al. Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase. Molecules 22(2), 276 (2017).