An endogenous metabolite of L-tryptophan
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L-Tryptophanamide (hydrochloride)

Item No. 35769

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
αS-amino-1H-indole-3-propanamide, monohydrochloride
CAS Number
5022-65-1
Molecular Formula
C11H13N3O • HCl
Formula Weight
239.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlEthanol: insolPBS (pH 7.2): 5 mg/ml
λmax
218 nm
SMILES
NC([C@@H](N)CC1=CNC2=CC=CC=C12)=O.Cl
InChi Code
InChI=1S/C11H13N3O.ClH/c12-9(11(13)15)5-7-6-14-10-4-2-1-3-8(7)10;/h1-4,6,9,14H,5,12H2,(H2,13,15);1H/t9-;/m0./s1
InChi Key
WOBDANBSEWOYKN-FVGYRXGTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $32

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    5 g

    $148

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    10 g

    $264

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    25 g

    $618

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    Product Description

    L-Tryptophanamide is an endogenous metabolite of L-tryptophan (Item No. 29600).1 It inhibits proliferation of, and induces necrosis in, human retinal pigment epithelium cells (HRPECs). Levels of L-tryptophanamide are increased in patients with wet age-related macular degeneration (wAMD) presenting with choroidal neovascularization compared with wAMD patients presenting with polypoidal choroidal neovascularization.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Deng, Y., Shuai, P., Wang, H., et al. Untargeted metabolomics for uncovering plasma biological markers of wet age-related macular degeneration. Aging (Albany NY) 13(10), 13968-14000 (2021).