A ganglioside
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Alternative(s)
25487Ganglioside GD2 (ammonium salt)
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Ganglioside GD2 (bovine buttermilk) (ammonium salt)

Item No. 35774

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Disialoganglioside GD2
  • Ganglioside GD2, Disialo
Molecular Formula
C83H148N4O34 • 2NH4 (for tricosanoyl)
Formula Weight
1746.1
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol:Water (2:1:0.1): Soluble
SMILES
O[C@@H]1[C@@H](O)[C@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC([R])=O)O[C@H](CO)[C@@]1([H])O[C@@H]2O[C@H](CO)[C@H](O[C@@]3([H])[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)[C@H](O[C@@]4(C([O-])=O)O[C@]([C@H](O)[C@@H](CO)O[C@@]5(C([O-])=O)O[C@]([C@H](O)[C@H](O)CO)([H])[C@H](NC(C)=O)[C@@H](O)C5)([H])[C@H](NC(C)=O)[C@@H](O)C4)[C@H]2O.[NH4+].[NH4+]
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $909

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    Product Description

    Ganglioside GD2 is a glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is frequently expressed on tumor cells of neuroectodermal origin, including neuroblastomas.1 This product is a semisynthetic mixture of ganglioside GD2 produced from buttermilk and is thus free from potential contamination with transmissible spongiform encephalopathies (TSE). It contains ganglioside GD2 molecular species with primarily C23:0, C22:0, and C24:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Barker, E.L., Mueller, B.M., Handgretinger, R., et al. Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cells. Cancer Res. 51(1), 144-149 (1991).