A diphenylmethane dye
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Auramine O

Item No. 35787

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4,4′-carbonimidoylbis[N,N-dimethyl-benzenamine, monohydrochloride
CAS Number
2465-27-2
Synonyms
  • AO
  • AuO
Molecular Formula
C17H21N3 • HCl
Formula Weight
303.8
Emission
550 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
λmax
204, 307, 430 nm
SMILES
N=C(C1=CC=C(N(C)C)C=C1)C2=CC=C(N(C)C)C=C2.Cl
InChi Code
InChI=1S/C17H21N3.ClH/c1-19(2)15-9-5-13(6-10-15)17(18)14-7-11-16(12-8-14)20(3)4;/h5-12,18H,1-4H3;1H
InChi Key
KSCQDDRPFHTIRL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

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    Cayman Chemical
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    Product Description

    Auramine O is a diphenylmethane dye.1 It displays absorbance/emission maxima of 432/550 nm, respectively. Auramine O is an acid-fast dye that has been used in the staining of various bacteria, including M. tuberculosis.2 It induces autophagy in, and promotes migration of, A549 lung cancer cells.3 Formulations containing auramine O were previously used as food additives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    2. Ryan, G.J., Shapiro, H.M., and Lenaerts, A.J. Improving acid-fast fluorescent staining for the detection of mycobacteria using a new nucleic acid staining approach. Tuberculosis (Edinb) 94(5), 511-518 (2014).

    3. Tung, J.-C., Huang, W.-C., Yang, J.-C., et al. Auramine O, an incense smoke ingredient, promotes lung cancer malignancy. Environ. Toxicol. 32(11), 2379-2391 (2017).