A citrullinated and biotinylated peptide derivative of filaggrin
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CCP-biotin Peptide (non-cyclized)

Item No. 35876

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized)
  • Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized)
MW
2,569.7 Da
Formulation (Request formulation change)
This vial contains 1 mg of lyophilized peptide
Peptide Sequence
Biotin-HQCHQESTXGRSRGRCGRSGS (X=Citrulline)
UniProt Accession №
P20930
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $248

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    Product Description

    CCP-biotin peptide (non-cyclized) is a biotinylated and non-cyclized version of circular citrullinated peptide (CCP).1 The sequence corresponds to amino acids 447-467 of human filaggrin but contains Q447H, S449C, G459R, E460G, and S462C substitutions and is citrullinated at arginine 455. Cayman's CCP-biotin Peptide (non-cyclized) is intended for use in the detection of anti-citrulline autoantibodies, which may bind the linear peptide.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Won, P., Kim, Y., Jung, H., et al. Pathogenic role of circulating citrullinated antigens and anti-cyclic monoclonal citrullinated peptide antibodies in rheumatoid arthritis. Front. Immunol. 12, 692242 (2021).