A dicarboxylic fatty acid
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Hexadecanedioic Acid

Item No. 36000

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
505-54-4
Synonyms
  • FA 16:1;O2
  • HDA
  • NSC 15164
  • Thapsic Acid
  • 1,16-Hexadecadioic Acid
  • 1,16-Hexadecanedioic Acid
  • α,ω-Hexadecanedioic Acid
Molecular Formula
C16H30O4
Formula Weight
286.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 12 mg/mlEthanol: Slightly soluble
SMILES
O=C(CCCCCCCCCCCCCCC(O)=O)O
InChi Code
InChI=1S/C16H30O4/c17-15(18)13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(19)20/h1-14H2,(H,17,18)(H,19,20)
InChi Key
QQHJDPROMQRDLA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $37

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    5 g

    $82

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    10 g

    $145

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    25 g

    $270

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    Product Description

    Hexadecanedioic acid is a dicarboxylic fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark and soil.1,2 It stimulates mitochondrial respiration and decreases the production of reactive oxygen species (ROS) induced by rotenone (Item No. 13995) in isolated rat liver mitochondria when used at concentrations of 100 and 40 µM, respectively.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Karnaouri, A., Lange, H., Crestini, C., et al. Chemoenzymatic fractionation and characterization of pretreated birch outer bark. ACS Sustainable Chem. Eng. 4(10), 5289-5302 (2016).

    2. Hamer, U., Rumpel, C., and Dignac, M.-F. Cutin and suberin biomarkers as tracers for the turnover of shoot and root derived organic matter along a chronosequence of Ecuadorian pasture soils. Eur. J. Soil Sci. 63(6), 808-819 (2012).

    3. Sememova, A.A., V.N., S., Pavlova, S.I., et al. ω-Hydroxypalmitic and α,ω-hexadecanedioic acids as activators of free respiration and inhibitors of H2O2 generation in liver mitochondria. Biochem. Moscow Suppl. Ser. A 14(1), 24-33 (2020).