An alkaline phosphatase inhibitor
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4-Aminobenzylphosphonic Acid

Item No. 36029

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
P-[(4-aminophenyl)methyl]-phosphonic acid
CAS Number
5424-27-1
Synonyms
  • 4-ABPA
  • NSC 12117
Molecular Formula
C7H10NO3P
Formula Weight
187.1
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
1 M NH4OH: 1 mg/mlDMF: Slightly soluble
λmax
240 nm
SMILES
O=P(O)(CC1=CC=C(C=C1)N)O
InChi Code
InChI=1S/C7H10NO3P/c8-7-3-1-6(2-4-7)5-12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)
InChi Key
NEKHKXMBGWNTOO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $86

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    500 mg

    $163

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    1 g

    $307

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    Product Description

    4-Aminobenzylphosphonic acid is an inhibitor of alkaline phosphatase (Ki = 1.1 mM for the bovine intestine enzyme).1 It has been used in affinity chromatography for the purification of alkaline phosphatase. 4-Aminobenzylphosphonic acid has also been used in electrochemical modification of glassy carbon electrodes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Landt, M., Boltz, S.C., and Butler, L.G. Alkaline phosphatase: Affinity chromatography and inhibition by phosphonic acids. Biochemistry 17(5), 915-919 (1978).

    2. Benjamin, O.D., Weissmann, M., and Bélanger, D. Electrochemical modification of carbon electrode with benzylphosphonic groups. Electrochim. Acta 122, 210-217 (2014).