An antiviral agent
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Triazavirin

Item No. 36052

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-(methylthio)-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4(6H)-one, monosodium, dihydrate
CAS Number
928659-17-0
Synonyms
  • Riamilovir
  • TZV
Molecular Formula
C5H3N6O3S • Na [2H2O]
Formula Weight
286.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 5 mg/mlEthanol: insolPBS (pH 7.2): 3 mg/ml
λmax
216, 254, 359 nm
SMILES
O=C1C([N+]([O-])=O)=N[N-]C2=NC(SC)=NN12.[Na+].O.O
InChi Code
InChI=1S/C5H4N6O3S.Na.2H2O/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5;;;/h1H3,(H,6,8,9,12);;2*1H2/q;+1;;/p-1
InChi Key
DARSMUGUKCGKHQ-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    50 mg

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    100 mg

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    Cayman Chemical
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    Product Description

    Triazavirin is an antiviral agent.1 In vivo, triazavirin (1 mg/kg) inhibits lung viral accumulation in a mouse model of H5N1 influenza A infection. Triazavirin (20 mg/kg) inhibits platelet aggregation in a rat model of LPS-induced hypercytokinemia.2 Formulations containing triazavirin have been used in the treatment of influenza.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Loginova, S.I., Borisevich, S.V., Maksimov, V.A., et al. Therapeutic efficacy of Triazavirin, a novel Russian chemotherapeutic, against influenza virus A (H5N1). Antibiot. Khimioter. 56(1-2), 10-12 (2011).

    2. Spasov, A.A., Kucheryavenko, A.F., Sirotenko, V.S., et al. Antiplatelet activity of riamilovir under conditions of lipopolysaccharide intoxication. Bull. Exp. Biol. Med. 173(1), 41-45 (2022).