An aggregation-induced emission fluorogen
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TTAPE-Me

Item No. 36068

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2′,2′′,2′′′-[1,2-ethenediylidenetetrakis(4,1-phenyleneoxy)]tetrakis[N,N,N-trimethyl-ethanaminium, tetrabromide
CAS Number
1219133-97-7
Synonyms
  • 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene
Molecular Formula
C46H68N4O4 • 4Br
Formula Weight
1060.7
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
256 nm
SMILES
C[N+](C)(C)CCOC(C=C1)=CC=C1/C(C(C=C2)=CC=C2OCC[N+](C)(C)C)=C(C3=CC=C(C=C3)OCC[N+](C)(C)C)\C4=CC=C(C=C4)OCC[N+](C)(C)C.[Br-].[Br-].[Br-].[Br-]
InChi Code
InChI=1S/C46H68N4O4.4BrH/c1-47(2,3)29-33-51-41-21-13-37(14-22-41)45(38-15-23-42(24-16-38)52-34-30-48(4,5)6)46(39-17-25-43(26-18-39)53-35-31-49(7,8)9)40-19-27-44(28-20-40)54-36-32-50(10,11)12;;;;/h13-28H,29-36H2,1-12H3;4*1H/q+4;;;;/p-4
InChi Key
AFLMSZYBOYHTEF-UHFFFAOYSA-J
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $219

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    10 mg

    $395

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    25 mg

    $821

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    Product Description

    TTAPE-Me is an aggregation-induced emission (AIE) fluorogen.1,2,3 It has been used to detect anionic phospholipids, including cardiolipin, phosphatidylglycerol (PG), and phosphatidylserine (PS), nucleic acids, and the anionic polysaccharide heparin.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pyrshev, K., Yesylevskyy, S., and Bogdanov, M. TTAPE-Me dye is not selective to cardiolipin and binds to common anionic phospholipids nonspecifically. Biophys. J. 120(17), 3776-3786 (2021).

    2. Hong, Y., Chen, S., Leung, C.W.T., et al. Water-soluble tetraphenylethene derivatives as fluorescent "light-up" probes for nucleic acid detection and their applications in cell imaging. Chem. Asian J. 8(8), 1806-1812 (2013).

    3. Wang, Y.J., Lin, L., Zhang, X., et al. Selective, switchable fluorescent probe for heparin based on aggregation-induced emission. Anal. Biochem. 514, 48-54 (2016).