A flavonoid with antiproliferative activity
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3-hydroxy-9,10-Dimethoxypterocarpan

Item No. 36152

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6aR,11aR-dihydro-9,10-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol
CAS Number
73340-41-7
Synonyms
  • (–)-Methylnissolin
Molecular Formula
C17H16O5
Formula Weight
300.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetone: solubleChloroform: solubleDichloromethane: solubleDMSO: solubleEthyl Acetate: soluble
SMILES
COC1=C2O[C@]3([H])[C@](COC4=CC(O)=CC=C43)([H])C2=CC=C1OC
InChi Code
InChI=1S/C17H16O5/c1-19-13-6-5-10-12-8-21-14-7-9(18)3-4-11(14)15(12)22-16(10)17(13)20-2/h3-7,12,15,18H,8H2,1-2H3/t12-,15-/m0/s1
InChi Key
UOVGCLXUTLXAEC-WFASDCNBSA-N
Origin
Plant/Astragalus membranaceus
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $83

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    5 mg

    $269

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    10 mg

    $413

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    25 mg

    $825

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    Product Description

    3-hydroxy-9,10-Dimethoxypterocarpan is a flavonoid that has been found in A. membranaceus and has antiproliferative activity.1 It inhibits PDGF-BB-induced proliferation of, and DNA synthesis in, A-10 vascular smooth muscle cells (IC50s = 10 and 1 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Onhawara, S., Okuma, Y., Uehara, T., et al. Astrapterocarpan isolated from Astragalus membranaceus inhibits proliferation of vascular smooth muscle cells. Eur. J. Pharmacol. 525(1-3), 41-47 (2005).