A sesquiterpene with anticancer activity
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Isomer(s)
24910(+)-Nootkatone 34294α-Cyperone
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Aristolone

Item No. 36157

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1aR,4,5,6,7R,7aR,7bS-octahydro-1,1,7,7a-tetramethyl-2H-cyclopropa[a]naphthalen-2-one
CAS Number
25274-27-5
Synonyms
  • (–)-Aristolone
  • Aristofone
Molecular Formula
C15H22O
Formula Weight
218.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetone: solubleChloroform: solubleDichloromethane: solubleDMSO: solubleEthyl Acetate: soluble
SMILES
C[C@@]12[C@@]3([H])[C@](C(C=C1CCC[C@H]2C)=O)([H])C3(C)C
InChi Code
InChI=1S/C15H22O/c1-9-6-5-7-10-8-11(16)12-13(14(12,2)3)15(9,10)4/h8-9,12-13H,5-7H2,1-4H3/t9-,12-,13+,15+/m1/s1
InChi Key
UGVIZCBJCSXBCJ-JWFUOXDNSA-N
Origin
Plant/Aristolochia manshuriensis
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $44

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    10 mg

    $84

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    25 mg

    $196

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    50 mg

    $369

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    Product Description

    Aristolone is a sesquiterpene that has been found in L. communis and has anticancer activity.1 It is cytotoxic to H460 lung, ES-2 ovarian, and DU145 prostate cancer cells (IC50s = 51.3, 61.5, and 58 µg/ml, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Deng, Z., Zhong, H., Cui, S., et al. Cytotoxic sesquiterpenoids from the fruits of Lindera communis. Fitoterapia 82(7), 1044-1046 (2011).