A secondary bile acid
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5α-Cholanic Acid-3,6-dione

Item No. 36184

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5α)-3,6-dioxo-cholan-24-oic acid
CAS Number
6929-22-2
Synonyms
  • NSC 18165
Molecular Formula
C24H36O4
Formula Weight
388.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: soluble
SMILES
C[C@@]12[C@]3([H])[C@](CC([C@@]1([H])CC(CC2)=O)=O)([H])[C@@]4([H])[C@](CC3)([C@]([C@@H](CCC(O)=O)C)([H])CC4)C
InChi Code
InChI=1S/C24H36O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14,16-20H,4-13H2,1-3H3,(H,27,28)/t14-,16+,17-,18+,19+,20-,23-,24-/m1/s1
InChi Key
AWINBLVINXVKTE-DLKBGQMWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    1 mg

    $98

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    5 mg

    $440

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    10 mg

    $781

    Add
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    Product Description

    5α-Cholanic Acid-3,6-dione is a secondary bile acid.1 Levels of 5α-cholanic acid-3,6-dione are decreased in the large intestinal contents of germ-free mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dempsey, J.L., Wang, D., Siginir, G., et al. Pharmacological activation of PXR and CAR downregulates distinct bile acid-metabolizing intestinal bacteria and alters bile acid homeostasis. Toxicol. Sci. 168(1), 40-60 (2019).