A potential impurity in commercial preparations of cefazolin
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7-[1-(1H)-Tetrazolylacetamido]desacetoxycephalosporanic Acid

Item No. 36228

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6R-trans)-3-methyl-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
56842-77-4
Synonyms
  • Cefazolin Impurity H
Molecular Formula
C11H12N6O4S
Formula Weight
324.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/ml
SMILES
[H][C@]12SCC(C)=C(C(O)=O)N1C([C@H]2NC(CN3N=NN=C3)=O)=O
InChi Code
InChI=1S/C11H12N6O4S/c1-5-3-22-10-7(9(19)17(10)8(5)11(20)21)13-6(18)2-16-4-12-14-15-16/h4,7,10H,2-3H2,1H3,(H,13,18)(H,20,21)/t7-,10-/m1/s1
InChi Key
DGYURGWZOSQCFG-GMSGAONNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    7-[1-(1H)-Tetrazolylacetamido]desacetoxycephalosporanic acid is a potential impurity in commercial preparations of the cephalosporin antibiotic cefazolin.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, S., Yao, S., Zhang, H., et al. Determination of relative response factors of cefazolin impurities by quantitative NMR. AAPS PharmSciTech 18(6), 1895-1900 (2017).