A fluorescently labeled form of dGTP
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Fluorescein-12-dGTP

Item No. 36235

Technical Information
Formal Name
4-((6-((3-(2-amino-7-((2R,4S,5R)-4-hydroxy-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)prop-2-yn-1-yl)amino)-6-oxohexyl)carbamoyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
Synonyms
  • Fluorescein-12-2'-deoxyguanosine-5'-triphosphate
Molecular Formula
C41H41N6O20P3
Formula Weight
Purity
≥95%
Emission
517 nm
Excitation
498 nm
A solution in 1 mM tris buffer (pH 7.5)
Water: Soluble
SMILES
O=C(CCCCCNC(C1=CC=C(C(O)=O)C(C2=C(C=C3)C(OC4=C2C=CC(O)=C4)=CC3=O)=C1)=O)NCC#CC5=CN([C@]6([H])O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)C6)C7=C5C(NC(N)=N7)=O.O=C(CCCCCNC(C8=CC=C(C9=C(C=C%10)C(OC%11=C9C=CC(O)=C%11)=CC%10=O)C(C(O)=O)=C8)=O)NCC#CC%12=CN([C@]%13([H])O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)C%13)C%14=C%12C(NC(N)=N%14)=O
InChi Code
InChI=1S/2C41H41N6O20P3/c42-41-45-37-35(39(53)46-41)22(19-47(37)34-18-29(50)32(65-34)20-63-69(59,60)67-70(61,62)66-68(56,57)58)5-4-14-43-33(51)6-2-1-3-13-44-38(52)21-7-10-25(40(54)55)28(15-21)36-26-11-8-23(48)16-30(26)64-31-17-24(49)9-12-27(31)36;42-41-45-37-35(39(53)46-41)22(19-47(37)34-18-29(50)32(65-34)20-63-69(59,60)67-70(61,62)66-68(56,57)58)5-4-14-43-33(51)6-2-1-3-13-44-38(52)21-7-10-25(28(15-21)40(54)55)36-26-11-8-23(48)16-30(26)64-31-17-24(49)9-12-27(31)36/h2*7-12,15-17,19,29,32,34,48,50H,1-3,6,13-14,18,20H2,(H,43,51)(H,44,52)(H,54,55)(H,59,60)(H,61,62)(H2,56,57,58)(H3,42,45,46,53)/t2*29-,32+,34+/m00/s1
InChi Key
PHDPFZPYRONPJO-PBJWHMRYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Fluorescein-12-dGTP is a fluorescently labeled form of the nucleotide 2'-deoxyguanosine-5'-triphosphate (dGTP). It displays excitation/emission maxima of 498/517 nm, respectively. Fluorescein-12-dATP has been used to label DNA in FRET genotyping applications.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Duan, X., Yue, W., Liu, L., et alSingle-nucleotide polymorphism (SNP) genotyping using cationic conjugated polymers in homogeneous solution. Nat. Protoc. 4(6), 984-991 (2009).