A bile pigment
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Biliverdin (technical grade)

Item No. 36337

Technical Information
Formal Name
3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
CAS Number
114-25-0
Synonyms
  • NSC 62793
Molecular Formula
C33H34N4O6
Formula Weight
Purity
≥70%
A solid
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
OC(CCC1=C(/C=C2C(CCC(O)=O)=C(C)C(/C=C3NC(C(C=C)=C\3C)=O)=N/2)NC(/C=C4NC(C(C)=C\4C=C)=O)=C1C)=O
InChi Code
InChI=1S/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-
InChi Key
QBUVFDKTZJNUPP-BBROENKCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Biliverdin is a porphyrin bile pigment and precursor in the biosynthesis of bilirubin (Item No. 17161).1,2 It is formed via oxidative catabolism of heme by heme oxygenase-1 (HO-1) and further reduced to bilirubin by biliverdin reductase. Biliverdin has antioxidant activity in oxygen radical absorbance capacity (ORAC) and Trolox equivalent absorbance capacity (TEAC) assays when used at concentrations greater than 0.5 µM.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, Y., Moënne-Loccoz, P., Loehr, T.M., et alHeme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents. The Journal of Biological Chemisty 272, 6909-6917 (1997).

    2. Maines, M.D. The heme oxygenase system: A regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37, 517-554 (1997).

    3. Mölzer, C., Huber, H., Steyrer, A., et alIn vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles. Free Radic. Res. 46(11), 1369-1377 (2012).