A derivative of DL-tryptophan
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N-acetyl-DL-Tryptophan

Item No. 36399

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-acetyl-tryptophan
CAS Number
87-32-1
Synonyms
  • DL-N-Acetyltryptophan
  • DL-NAT
  • NSC 49124
Molecular Formula
C13H14N2O3
Formula Weight
246.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 15 mg/mlEthanol: Slightly soluble
λmax
222, 282, 291 nm
SMILES
O=C(C(CC1=CNC2=C1C=CC=C2)NC(C)=O)O
InChi Code
InChI=1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)
InChi Key
DZTHIGRZJZPRDV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $40

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    25 g

    $65

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    50 g

    $119

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    100 g

    $217

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    Product Description

    N-acetyl-DL-Tryptophan (DL-NAT) is a derivative of the amino acid DL-tryptophan (Item No. 31210) and a racemic mixture of L-NAT and D-NAT.1 It protects against hydrogen peroxide-induced cell death of NSC-34 motoneurons in an in vitro model of amyotrophic lateral sclerosis (ALS; IC50 = 1 µM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sirianni, A.C., Jiang, J., Zeng, J., et al. N-acetyl-L-tryptophan, but not N-acetyl-D-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis. J. Neurochem. 135(5), 956-968 (2015).