An antibiotic
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Minosaminomycin

Item No. 36406

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[[(2S)-3-[(4R)-2-amino-4,5-dihydro-1H-imidazol-4-yl]-2-[[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]amino]-1-oxopropyl]amino]-1-deoxy-4-O-(2,4-diamino-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl)-D-myo-inositol
CAS Number
51746-09-9
Synonyms
  • MSM
Molecular Formula
C25H46N8O10
Formula Weight
618.7
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: solubleWater: soluble
SMILES
O=C(C(CC(C)C)NC(NC(CC1CN=C(N)N1)C(NC2C(C(C(C(C2O)O)OC3OC(C(CC3N)N)C)O)O)=O)=O)O
InChi Code
InChI=1S/C25H46N8O10/c1-8(2)4-14(22(39)40)32-25(41)31-13(5-10-7-29-24(28)30-10)21(38)33-15-16(34)18(36)20(19(37)17(15)35)43-23-12(27)6-11(26)9(3)42-23/h8-20,23,34-37H,4-7,26-27H2,1-3H3,(H,33,38)(H,39,40)(H3,28,29,30)(H2,31,32,41)
InChi Key
UDZJEGDQBWDMOF-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp. MA514-A1
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $616

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    Product Description

    Minosaminomycin is an antibiotic that has been found in Streptomyces.1 It is active against M. smegmatis and M. phlei (MICs = 1.56 and 6.25 µg/ml, respectively). Minosaminomycin (1 µM) inhibits the binding of formyl-Met-tRNA (fMet-tRNA) to ribosomes in the presence of the AUG trinucleotide by 96% in a cell-free assay and inhibits Mycobacterium protein synthesis when used at a concentration of 100 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hamada, M., Kondo, S., Yokoyama, T., et al. Letter: Minosaminomycin, a new antibiotic containing myo-inosamine. J. Antibiot. (Tokyo) 27(1), 81-83 (1974).

    2. Suzukake, K., and Hori, M. Biochemical study of minosaminomycin in relation to the kasugamycin group antibiotics. J. Antibiot. (Tokyo) 30(2), 132-140 (1977).