A phytoestrogen and an active metabolite of diadzein
Related Products
Parent Compound(s)
10005166Daidzein
Technical Support & Resources

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O-Desmethylangolensin

Item No. 36435

Technical Information
Formal Name
1-(2,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)-1-propanone
CAS Number
21255-69-6
Synonyms
  • O-DMA
Molecular Formula
C15H14O4
Formula Weight
Purity
≥95%
A solid
DMSO: solubleMethanol: soluble
SMILES
O=C(C(C)C1=CC=C(C=C1)O)C2=CC=C(C=C2O)O
InChi Code
InChI=1S/C15H14O4/c1-9(10-2-4-11(16)5-3-10)15(19)13-7-6-12(17)8-14(13)18/h2-9,16-18H,1H3
InChi Key
JDJPNKPFDDUBFV-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    O-Desmethylangolensin (O-DMA) is a phytoestrogen and an active metabolite of daidzein (Item No. 10005166).1 It is formed from daidzein by gut microbiota. O-DMA (2.5-50 µM) is cytotoxic to MDA-MB-231 cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frankenfeld, C.L. O-desmethylangolensin: The importance of equol’s lesser known cousin to human health. Adv. Nutr. 2(4), 317-324 (2011).

    2. Magee, P.J., McGlynn, H., and Rowland, I.R. Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro. Cancer Lett. 208(1), 35-41 (2004).