A dicarboxylic acid and derivative of 3-methylglutaric acid
Related Products
Isomer(s)
343573-Methylglutaric Acid
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Lipids
Fatty Acids

Research Area

Cancer

2-Methylglutaric Acid

Item No. 36440

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-methyl-pentanedioic acid
CAS Number
617-62-9
Synonyms
  • FA 6:1;O2
  • α-Methylglutaric Acid
  • NSC 5941
  • NSC 408456
Molecular Formula
C6H10O4
Formula Weight
146.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 16 mg/mlEthanol: Slightly solublePBS (pH 7.2): 10 mg/ml
SMILES
O=C(CCC(C)C(O)=O)O
InChi Code
InChI=1S/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)
InChi Key
AQYCMVICBNBXNA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $33

    Add

    5 g

    $98

    Add

    10 g

    $181

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    2-Methylglutaric acid is a dicarboxylic acid and derivative of the L-leucine metabolite 3-methylglutaric acid (Item No. 34357) that has been found in K. excelsa honey.1 2-Methylglutaric acid levels are decreased by the methylation inhibitor 5-aza-2'-deoxycytidine (decitabine; Item No. 11166) in several bladder cancer cell lines.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wilkins, A.L., Lu, Y., and Tan, S.-T. Extractives from New Zealand honeys. 5. Aliphatic dicarboxylic acids in New Zealand rewarewa (Knightea excelsa) honey. J. Agric. Food Chem. 43, 3021-3025 (1995).

    2. Ambati, C.R., Vantaku, V., Donepudi, S.R., et al. Measurement of methylated metabolites using Liquid Chromatography-Mass Spectrometry and its biological application. Anal. Methods 11(1), 49-57 (2019).