A dicarboxylic fatty acid
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2-Hydroxyadipic Acid

Item No. 36482

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-hydroxy-hexanedioic acid
CAS Number
18294-85-4
Synonyms
  • FA 6:1;O3
  • α-Hydroxyadipic Acid
Molecular Formula
C6H10O5
Formula Weight
162.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 1 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O=C(CCCC(C(O)=O)O)O
InChi Code
InChI=1S/C6H10O5/c7-4(6(10)11)2-1-3-5(8)9/h4,7H,1-3H2,(H,8,9)(H,10,11)
InChi Key
OTTXIFWBPRRYOG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $37

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    10 mg

    $61

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    50 mg

    $217

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    100 mg

    $403

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    Cayman Chemical
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    Product Description

    2-Hydroxyadipic acid is a dicarboxylic fatty acid. Levels of 2-hydroxyadipic acid are decreased in tumor tissue from patients with esophageal squamous cell carcinoma.1 Urinary 2-hydroxyadipic acid levels are increased in patients with 2-ketoadipic aciduria, a disorder characterized by a deficiency in lysine, hydroxylysine, and tryptophan degradation.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, Z., Gao, Y., Huang, X., et al. Tissue-based metabolomics reveals metabolic biomarkers and potential therapeutic targets for esophageal squamous cell carcinoma. J. Pharm. Biomed. Anal. 197, 113937 (2021).

    2. Stiles, A.R., Venturoni, L., Mucci, G., et al. New cases of DHTKD1 mutations in patients with 2-ketoadipic aciduria. JIMD Reports. Volume 25 25, 15-19 (2015).