A phenothiazine derivative
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Carfenazine

Item No. 36486

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-1-propanone
CAS Number
2622-30-2
Synonyms
  • Carphenazine
  • NSC 71755
Molecular Formula
C24H31N3O2S
Formula Weight
425.6
Purity
≥90%
Formulation (Request formulation change)
A 10 mg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
O=C(CC)C1=CC=C2SC3=C(N(CCCN4CCN(CC4)CCO)C2=C1)C=CC=C3
InChi Code
InChI=1S/C24H31N3O2S/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28/h3-4,6-9,18,28H,2,5,10-17H2,1H3
InChi Key
XZSMZRXAEFNJCU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $72

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    5 mg

    $318

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    10 mg

    $565

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    Product Description

    Carfenazine is a phenothiazine derivative.1 It induces hypothermia in rats when administered at a dose of 10 mg/kg. Formulations containing carfenazine have previously been used in the treatment of schizophrenia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yehuda, S., and Frommer, R. The possible role of dopamine in phenothiazine-induced hypothermia in rats: An application to DA hypothesis of schizophrenia. Int. J. Neurosci. 7(2), 67-72 (1977).