An Analytical Reference Standard
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10004272GW 501516
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GW 501516

Item No. 36516

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • GW 1516
Technical Information
Formal Name
2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid
CAS Number
317318-70-0
Molecular Formula
C21H18F3NO3S2
Formula Weight
453.5
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:2): .5 mg/mlEthanol: 12 mg/mlPBS (pH 7.2): insol
λmax
318 nm
SMILES
CC1=CC(SCC2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=CC=C1OCC(O)=O
InChi Code
InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)
InChi Key
YDBLKRPLXZNVNB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    GW 501516 (Item No. 36516) is an analytical reference standard categorized as a peroxisome proliferator-activated receptor δ (PPARδ) agonist.1 Formulations containing GW 501516 have been used to enhance physical performance in athletes. This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 10004272).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Thevis, M., Möller, I., Thomas, A., et al. Characterization of two major urinary metabolites of the PPARδ-agonist GW1516 and implementation of the drug in routine doping controls. Anal. Bioanal. Chem. 396(7), 2479-2491 (2010).

    Product Citations

    Chen, S.-T., Shi, W.-W., Lin, Y.-Q., et al. Embryo-derive TNF promotes decidualization via fibroblast activation. Elife 12, e82970 (2023).