A phenolic compound
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Isomer(s)
365353-Methoxycatechol
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2-Methoxyhydroquinone

Item No. 36537

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-methoxy-1,4-benzenediol
CAS Number
824-46-4
Synonyms
  • o-Methoxyhydroquinone
  • MHQ
  • MOHQ
Molecular Formula
C7H8O3
Formula Weight
140.1
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/ml
SMILES
OC1=CC=C(C(OC)=C1)O
InChi Code
InChI=1S/C7H8O3/c1-10-7-4-5(8)2-3-6(7)9/h2-4,8-9H,1H3
InChi Key
LAQYHRQFABOIFD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 g

    $36

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    10 g

    $57

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    25 g

    $123

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    50 g

    $208

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    Product Description

    2-Methoxyhydroquinone is a phenolic compound. It reduces TNF-α-induced production of chemokine (C-C motif) ligand 2 (CCL2) in vitro with an IC50 value of 64.3 µM.1 2-Methoxyhydroquinone has been used as a precursor in the synthesis of the Hsp90 inhibitor geldanamycin (Item No. 13355).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Houser, K.R., Johnson, D.K., and Ishmael, F.T. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J. Inflamm. (Lond.) 9, 6 (2012).

    2. Qin, H.-L., and Panek, J.S. Total synthesis of the Hsp90 inhibitor geldanamycin. Org. Lett. 10(12), 2477-2479 (2008).