An inhibitor of MAO-A
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Eprobemide

Item No. 36604

Technical Information
Formal Name
4-chloro-N-[3-(4-morpholinyl)propyl]-benzamide
CAS Number
87940-60-1
Molecular Formula
C14H19ClN2O2
Formula Weight
Purity
≥98%
A solid
DMF: 25 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 0.5 mg/ml
λmax
237 nm
SMILES
O=C(C1=CC=C(C=C1)Cl)NCCCN2CCOCC2
InChi Code
InChI=1S/C14H19ClN2O2/c15-13-4-2-12(3-5-13)14(18)16-6-1-7-17-8-10-19-11-9-17/h2-5H,1,6-11H2,(H,16,18)
InChi Key
YYFGRAGNYHYWEZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    Eprobemide is an inhibitor of monoamine oxidase A (MAO-A).1 It reduces immobility time in a modified version of the forced swim test in rats when administered at a dose of 10 mg/kg.2 Formulations containing eprobemide have previously been used in the treatment of depression.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zaqgorevskii, V.A., Valdman, A.V., Kozlovskaya, M.M., et al. Search for antidepressants among benzamide derivatives. Khimiko-Farmatsevticheskii Zhurnal 23(11), 1304-1309 (1989).

    2. Bondarenko, N.A., Gorantcheva, J., Tyutyulkova, N., et al. Effect of some benzamide derivatives on stress-induced behavior and striatum dopamine receptors. Methods Find. Exp. Clin. Pharmacol. 10(7), 629-633 (1988).