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Menitazene (citrate)

Item No. 36634

Technical Information
Formal Name
N,N-diethyl-2-[(4-methylphenyl)methyl]-5-nitro-1H-benzimidazole-1-ethanamine, 2-hydroxy-1,2,3-propanetricarboxylate
Molecular Formula
C21H26N4O2 • C6H8O7
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 3 mg/mlDMSO: 2 mg/mlEthanol: insolPBS (pH 7.2): insol
λmax
243 nm
SMILES
CC(C=C1)=CC=C1CC(N2CCN(CC)CC)=NC3=C2C=CC([N+]([O-])=O)=C3.OC(CC(O)=O)(C(O)=O)CC(O)=O
InChi Code
InChI=1S/C21H26N4O2.C6H8O7/c1-4-23(5-2)12-13-24-20-11-10-18(25(26)27)15-19(20)22-21(24)14-17-8-6-16(3)7-9-17;7-3(8)1-6(13,5(11)12)2-4(9)10/h6-11,15H,4-5,12-14H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChi Key
BZSZTIMYGSCLBH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Menitazene (citrate) (Item No. 36634) is an analytical reference standard categorized as an opioid.1 Metonitazene has analgesic effects in mice. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ujváry, I., Christie, R., Evans-Brown, M., et alDARK classics in chemical neuroscience: Etonitazene and related benzimidazoles. ACS Chem. Neurosci. 12(7), 1072-1092 (2021).

    Product Citations

    Souza, K.A.O., Santos, N.C.B.F., Lanaro, R., et alMicro-QuEChERS extraction for broad-spectrum LC-QQQ-MS quantification of nitazene analogs in plasma: A validated method with casework application. Drug Test Anal. (2026).

    Hardwick, E.K., and Davidson, J.T. Structural characterization of nitazene analogs using electrospray ionization-tandem mass spectrometry (ESI-MS/MS). Drug Test Anal. (2025).

    Kozell, L.B., Eshleman, A.J., Wolfrum, K.M., et alPharmacology of newly identified nitazene variants reveals structural determinants of affinity, potency, selectivity for mu opioid receptors. Neuropharmacology 276, 110512 (2025).

    Leonard, A.C., Lenert-Mondou, C., Chayer, R., et alComputational design of dynamic biosensors for emerging synthetic opioids. BioRxiv (2025).