An antimicrobial peptide
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Parasin I (catfish) (trifluoroacetate salt)

Item No. 36724

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-lysylglycyl-L-arginylglycyl-L-lysyl-L-glutaminylglycylglycyl-L-lysyl-L-valyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-serine, trifluoroacetate salt
Molecular Formula
C82H154N34O24 • XCF3COOH
Formula Weight
2000.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
KGRGKQGGKVRAKAKTRSS-OH
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O=C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN[H])C(N[C@@H](CCC(N)=O)C(NCC(NCC(N[C@@H](CCCCN[H])C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCCN[H])C(N[C@H](C(N[C@@H](CCCCN[H])C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)C)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN[H])N[H].OC(C(F)(F)F)=O
InChi Code
InChI=1S/C82H154N34O24.C2HF3O2/c1-43(2)63(115-74(134)50(21-8-13-31-85)107-60(122)38-99-59(121)37-101-69(129)55(27-28-58(89)120)110-72(132)49(20-7-12-30-84)106-62(124)40-102-68(128)48(24-16-34-96-80(90)91)105-61(123)39-100-67(127)47(88)19-6-11-29-83)77(137)111-53(25-17-35-97-81(92)93)71(131)104-44(3)65(125)108-51(22-9-14-32-86)70(130)103-45(4)66(126)109-52(23-10-15-33-87)75(135)116-64(46(5)119)78(138)112-54(26-18-36-98-82(94)95)73(133)113-56(41-117)76(136)114-57(42-118)79(139)140;3-2(4,5)1(6)7/h43-57,63-64,117-119H,6-42,83-88H2,1-5H3,(H2,89,120)(H,99,121)(H,100,127)(H,101,129)(H,102,128)(H,103,130)(H,104,131)(H,105,123)(H,106,124)(H,107,122)(H,108,125)(H,109,126)(H,110,132)(H,111,137)(H,112,138)(H,113,133)(H,114,136)(H,115,134)(H,116,135)(H,139,140)(H4,90,91,96)(H4,92,93,97)(H4,94,95,98);(H,6,7)/t44-,45-,46+,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-,64-;/m0./s1
InChi Key
BTXXNWHYYHYHIK-OPRBQJJWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Parasin I is an antimicrobial peptide fragment from the N-terminal region of histone H2A in catfish (P. asotus) that is involved in host defense.1 It is formed from histone H2A by cathepsin D in the skin mucosa of wounded P. asotus. Parasin I is active against various Gram-positive and Gram-negative bacteria, as well as fungi (MICs = 1-2, 1-4, and 1-2 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cho, J.H., Park, I.Y., and Kim, S.C. Cathepsin D produces the potent antimicrobial peptide parasin I from histone H2A in scaleless fish skin. Peptides: The wave of the future 1049-1050 (2001).

    2. Park, I.Y., Park, C.B., Kim, M.S., et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 437(3), 258-262 (1998).