An esterified form of protectin D1
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Protectin D1 methyl ester

Item No. 36746

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid, methyl ester
CAS Number
934005-36-4
Synonyms
  • Neuroprotectin D1 methyl ester
  • NPD1 methyl ester
  • PD1 methyl ester
Molecular Formula
C23H34O4
Formula Weight
374.5
Purity
≥95%
Formulation (Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: 1 mg/ml
λmax
271, 282 nm
SMILES
CC/C=C\C[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\C/C=C\CCC(OC)=O
InChi Code
InChI=1S/C23H34O4/c1-3-4-11-16-21(24)18-13-9-10-14-19-22(25)17-12-7-5-6-8-15-20-23(26)27-2/h4,6-14,18-19,21-22,24-25H,3,5,15-17,20H2,1-2H3/b8-6-,10-9+,11-4-,12-7-,18-13-,19-14+/t21-,22+/m0/s1
InChi Key
ZWYWDYYLNRVEOD-UXJCUXGASA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 µg

    $160

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    25 µg

    $359

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    50 µg

    $678

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    Product Description

    Protectin D1 methyl ester is an esterified form of the specialized pro-resolving mediator protectin D1 (Item No. 10010390). It is an intermediate in the synthesis of protectin D1.1 Protectin D1 methyl ester (333 µg/kg) reduces infarct area and volume and increases blood vessel density in the tissue surrounding the infarct in a rat model of ischemic stroke induced by middle cerebral artery occlusion (MCAO).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rodriguez, A.R., and Spur, B.W. Total synthesis of the potent anti-inflammatory lipid mediator Protectin D1. Tetrahedron Lett. 55(43), 6011-6015 (2014).

    2. Bazan, N.G., Eady, T.N., Khoutorova, L., et al. Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke. Exp. Neurol. 236(1), 122-130 (2012).