A peptide substrate for PKC
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Myelin Basic Protein Peptide (mouse, bovine) (trifluoroacetate salt)

Item No. 36761

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt
Synonyms
  • Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu
  • MBP Peptide
Molecular Formula
C60H103N21O17 • XCF3COOH
Formula Weight
1390.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Peptide Sequence
QKRPSQRSKYL-OH
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O=C(N(CCC1)[C@@H]1C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CC(C=C2)=CC=C2O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H](N)CCC(N)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C60H103N21O17.C2HF3O2/c1-32(2)28-42(58(97)98)78-53(92)41(29-33-15-17-34(84)18-16-33)77-50(89)37(11-4-6-24-62)74-54(93)43(30-82)79-51(90)38(12-7-25-70-59(66)67)73-52(91)39(20-22-47(65)86)75-55(94)44(31-83)80-56(95)45-14-9-27-81(45)57(96)40(13-8-26-71-60(68)69)76-49(88)36(10-3-5-23-61)72-48(87)35(63)19-21-46(64)85;3-2(4,5)1(6)7/h15-18,32,35-45,82-84H,3-14,19-31,61-63H2,1-2H3,(H2,64,85)(H2,65,86)(H,72,87)(H,73,91)(H,74,93)(H,75,94)(H,76,88)(H,77,89)(H,78,92)(H,79,90)(H,80,95)(H,97,98)(H4,66,67,70)(H4,68,69,71);(H,6,7)/t35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-;/m0./s1
InChi Key
ZDBPQAQBILIIJK-FSUPYBCYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $32

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    5 mg

    $142

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    10 mg

    $252

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    25 mg

    $550

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    Product Description

    Myelin basic protein (MBP) peptide is a peptide substrate for PKC.1 It is selective for PKC over PKA, casein kinase 1 (CK1), CK2, phosphorylase kinase, and calcium/calmodulin-dependent protein kinase (CaMKII). MBP peptide has been used to monitor PKC activity in primary human renal artery smooth muscle cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yasuda, I., Kishimoto, A., Tanaka, S., et al. A synthetic peptide substrate for selective assay of protein kinase C. Biochem. Biophys. Res. Commun. 166(3), 1220-1227 (1990).

    2. Assender, J.W., Irenius, E., and Fredholm, B.B. Endothelin-1 causes a prolonged protein kinase C activation and acts as a co-mitogen in vascular smooth muscle cells. Acta Physiol. Scand. 157(4), 451-460 (1996).