A nonionic surfactant
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Product Type

Biochemicals

Research Area

Cell Biology

Ethylene Glycol monododecyl ether

Item No. 36857

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(dodecyloxy)-ethanol
CAS Number
4536-30-5
Synonyms
  • C12E1
  • EGDE
Molecular Formula
C14H30O2
Formula Weight
230.4
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 15 mg/ml
SMILES
OCCOCCCCCCCCCCCC
InChi Code
InChI=1S/C14H30O2/c1-2-3-4-5-6-7-8-9-10-11-13-16-14-12-15/h15H,2-14H2,1H3
InChi Key
SFNALCNOMXIBKG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $33

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    10 mg

    $63

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    50 mg

    $181

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    100 mg

    $294

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    Product Description

    Ethylene glycol monododecyl ether is a nonionic surfactant with a critical micelle concentration (CMC) of 27.5 µM at 25°C.1 It enhances the transdermal permeation of the antiemetic ondansetron across isolated porcine skin when used at a concentration of 160 mM, however, it decreases the viability of human epidermal keratinocytes and human dermal fibroblasts when used at a concentration of 160 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Islam, M.N., and Kato, T. Temperature dependence of the surface phase behavior and micelle formation of some nonionic surfactants. J. Phys. Chem. B 107(4), 965-971 (2003).

    2. Silva, S.M.C., Hu, L., Sousa, J.J.S., et al. A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondansetron HCl and diltiazem HCl. Eur. J. Pharm. Biopharm. 80(3), 663-673 (2012).