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Cannabidiolic Acid

Item No. 36871

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • CBDA
Technical Information
Formal Name
2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-6-pentyl-benzoic acid
CAS Number
1244-58-2
Molecular Formula
C22H30O4
Formula Weight
358.5
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 11 mg/mlDMSO: 14 mg/mlEthanol: 16 mg/ml
λmax
224, 270 nm
SMILES
OC1=C(C(O)=O)C(CCCCC)=CC(O)=C1[C@@H]2C=C(C)CC[C@H]2C(C)=C
InChi Code
InChI=1S/C22H30O4/c1-5-6-7-8-15-12-18(23)20(21(24)19(15)22(25)26)17-11-14(4)9-10-16(17)13(2)3/h11-12,16-17,23-24H,2,5-10H2,1,3-4H3,(H,25,26)/t16-,17+/m0/s1
InChi Key
WVOLTBSCXRRQFR-DLBZAZTESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

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    Cayman Chemical
    Explore All Cannabis Testing Resources
    Fit-for-Purpose CRMs & Analytical Standards
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    Product Description

    Cannabidiolic acid (Item No. 36871) is an analytical reference standard categorized as a phytocannabinoid.1,2 Cannabidiolic acid has anxiolytic-like and antinociceptive activities in mice.2,3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Taura, F., Morimoto, S., and Shoyama, Y. Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid. The Journal of Biological Chemisty 271(29), 17411-17416 (1996).

    2. ZagZoog, A., Mohamed, K.A., Kim, H.J.J., et al. In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa. Sci. Rep. 10(1), 20405 (2020).

    3. Vigli, D., Cosentino, L., Pellas, M., et al. Chronic treatment with cannabidiolic scid (CBDA) reduces thermal pain sensitivity in male mice and rescues the hyperalgesia in a mouse model of Rett syndrome. Neuroscience 453, 113-123 (2021).

    Product Citations

    Haase, A., and Morlock, G. Unmasking hazardous compounds in cannabidiol-containing oils using planar bioassays and high-resolution mass spectrometry. Talanta 302, 129273 (2025).