An endogenous myelin sheath peptide
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MOG Peptide (human, bovine) (acetate)

Item No. 36906

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-methionyl-L-α-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-prolyl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl-L-lysine, acetate
Synonyms
  • Myelin Oligodendrocyte Glycoprotein Peptide
Molecular Formula
C120H179N35O28S • XC2H4O2
Formula Weight
2592.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
MEVGWYRPPFSRVVHLYRNGK-OH
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CCCNC(N)=N)C(N4CCC[C@H]4C(N5CCC[C@H]5C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CNC=N6)C(N[C@H](C(N[C@@H](CC7=CC=C(O)C=C7)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CCCCN[H])C(O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N[H].CC(O)=O
InChi Code
InChI=1S/C120H179N35O28S.C2H4O2/c1-63(2)50-82(104(169)145-83(52-68-32-36-72(157)37-33-68)105(170)141-77(27-17-44-131-118(124)125)101(166)147-88(56-92(123)159)100(165)135-59-93(160)138-81(117(182)183)26-15-16-43-121)144-109(174)87(55-71-58-130-62-137-71)149-113(178)97(65(5)6)153-114(179)98(66(7)8)152-102(167)78(28-18-45-132-119(126)127)142-110(175)89(61-156)150-107(172)85(51-67-22-11-10-12-23-67)148-111(176)90-30-20-47-154(90)116(181)91-31-21-48-155(91)115(180)80(29-19-46-133-120(128)129)143-106(171)84(53-69-34-38-73(158)39-35-69)146-108(173)86(54-70-57-134-76-25-14-13-24-74(70)76)139-94(161)60-136-112(177)96(64(3)4)151-103(168)79(40-41-95(162)163)140-99(164)75(122)42-49-184-9;1-2(3)4/h10-14,22-25,32-39,57-58,62-66,75,77-91,96-98,134,156-158H,15-21,26-31,40-56,59-61,121-122H2,1-9H3,(H2,123,159)(H,130,137)(H,135,165)(H,136,177)(H,138,160)(H,139,161)(H,140,164)(H,141,170)(H,142,175)(H,143,171)(H,144,174)(H,145,169)(H,146,173)(H,147,166)(H,148,176)(H,149,178)(H,150,172)(H,151,168)(H,152,167)(H,153,179)(H,162,163)(H,182,183)(H4,124,125,131)(H4,126,127,132)(H4,128,129,133);1H3,(H,3,4)/t75-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,96-,97-,98-;/m0./s1
InChi Key
FDLLTWKXKGVGNT-RQWCQPARSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $219

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    1 mg

    $329

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    5 mg

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    10 mg

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    Product Description

    Myelin oligodendrocyte glycoprotein (MOG) peptide is an endogenous peptide truncation of MOG, which is found on the extracellular surface of myelin sheaths.1 When coupled to the antigen serotype HLA-DR2, MOG peptide reduces cortical and striatal infarct volumes, decreases sensorimotor impairments in tube- and corner turn tests, increases time spent investigating novel odors, and increases the duration of cage mate-directed calls in female, but not male, mice in a model of ischemic stroke induced by middle cerebral artery occlusion (MCAO).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pan, J., Palmateer, J., Schallert, T., et al. Novel humanized recombinant T cell receptor ligands protect the female brain after experimental stroke. Transl. Stroke Res. 5(5), 577-585 (2014).