A synthetic peptide
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

BMP2-derived Peptide (trifluoroacetate salt)

Item No. 36948

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Bone Morphogenic Protein 2-derived Peptide
  • KIPKASSVPTELSAISTLYL-NH2
Molecular Formula
C104H176N26O32S • XCF3COOH
Formula Weight
2334.8
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: soluble
SMILES
OC(C(F)(F)F)=O.[H]NCCCC[C@H](NC([C@@H]1CCCN1C([C@](NC([C@H](CCCCN[H])N[H])=O)([H])[C@H](CC)C)=O)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N2CCC[C@H]2C(N[C@@]([H])([C@@H](C)O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@](C(N[C@@H](CO)C(N[C@@]([H])([C@@H](C)O)C(N[C@H](C(N[C@@H](CC(C=C3)=CC=C3O)C(N[C@H](C(NCC(NCC(N[C@@H](CS[H])C(N)=O)=O)=O)=O)CC(C)C)=O)=O)CC(C)C)=O)=O)=O)([H])[C@H](CC)C)=O)C)=O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)C)=O
InChi Code
InChI=1S/C104H176N26O32S.C2HF3O2/c1-17-54(11)80(100(158)123-72(48-134)97(155)127-82(58(15)135)102(160)119-67(41-52(7)8)91(149)118-68(42-60-29-31-61(137)32-30-60)93(151)116-65(39-50(3)4)88(146)110-43-76(138)109-44-77(139)113-73(49-163)84(108)142)125-86(144)57(14)112-94(152)69(45-131)121-92(150)66(40-51(5)6)117-90(148)64(33-34-78(140)141)115-101(159)83(59(16)136)128-99(157)75-28-24-37-129(75)103(161)79(53(9)10)124-96(154)71(47-133)122-95(153)70(46-132)120-85(143)56(13)111-89(147)63(26-20-22-36-106)114-98(156)74-27-23-38-130(74)104(162)81(55(12)18-2)126-87(145)62(107)25-19-21-35-105;3-2(4,5)1(6)7/h29-32,50-59,62-75,79-83,131-137,163H,17-28,33-49,105-107H2,1-16H3,(H2,108,142)(H,109,138)(H,110,146)(H,111,147)(H,112,152)(H,113,139)(H,114,156)(H,115,159)(H,116,151)(H,117,148)(H,118,149)(H,119,160)(H,120,143)(H,121,150)(H,122,153)(H,123,158)(H,124,154)(H,125,144)(H,126,145)(H,127,155)(H,128,157)(H,140,141);(H,6,7)/t54-,55-,56-,57-,58+,59+,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,79-,80-,81-,82-,83-;/m0./s1
InChi Key
MVCAHZBYWFQCOH-OSYUKRHNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $44

    Add

    5 mg

    $185

    Add

    10 mg

    $326

    Add

    25 mg

    $703

    Add
    Product Description

    BMP2-derived peptide is a synthetic peptide that corresponds to residues 73-92 of bone morphogenetic protein 2 (BMP2) and has a role in osteogenesis.1 It increases alkaline phosphatase (ALP) activity in C3H/10T1/2 murine mesenchymal cells when used at concentrations of 100 and 200 µg/well. BMP2-derived peptide (100 µg/well) increases mRNA expression of the gene encoding osteocalcin in C3H/10T1/2 cells. It induces osteoblast-like cell differentiation and ectopic calcification when conjugated to an alginate gel in rats when administered via a submuscular implant.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Saito, A., Suzuki, Y., Ogata, S.I., et al. Activation of osteo-progenitor cells by a novel synthetic peptide derived from the bone morphogenetic protein-2 knuckle epitope. Biochim. Biophys. Acta 1651(1-2), 60-67 (2003).

    2. Saito, A., Suzuki, Y., Ogata, S.-I., et al. Prolonged ectopic calcification induced by BMP-2-derived synthetic peptide. J. Biomed. Mater. Res. A 70(1), 115-121 (2004).