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Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.
DOWNLOAD NOWBING is an antimicrobial peptide that has been found in Japanese medaka fish (O. laptipes) and is derived from vacuolar protein sorting-associated protein 13D-like (Vps13D).1 It is active against various Gram-negative and Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA; MICs = 4-64 µg/ml). BING is synergistic with the antibiotics ampicillin (Item Nos. 14417 | 35740), amoxicillin (Item No. 19188), and novobiocin (Item No. 18457) against P. aeruginosa and suppresses the development of resistance to kanamycin and ampicillin in E. coli. In vivo, BING increases the survival rate of O. laptipes infected with E. tarda.
WARNING This product is not for human or veterinary use.
1. BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression. Sci. Rep. 11(1), 12219 (2021).