For immunochemical detection of influenza A nucleoprotein
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Influenza A Nucleoprotein Monoclonal Antibody (Clone 7B4G10G8)

Item No. 37013

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Influenza A NP
  • Influenza A Nucleocapsid Protein
Clone Designation
7B4G10G8
MW
56 kDa
Formulation (Request formulation change)
50 or 100 µl of protein A-affinity purified recombinant monoclonal antibody
Storage Buffer
0.2 μm filtered solution in PBS
Host
Mouse
Isotype
IgG2b
Applications
ELISA, WB
Cross Reactivity
(+) Nucleocapsid protein(-) Insect cell lysate
Species Reactivity
(+) H1N1, H7N9 (A/Anhui/1/2013)(+) H7N9 (A/Shanghai/1/2013)
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    50 µl

    $206

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    100 µl

    $329

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    Product Description

    Influenza A nucleoprotein is a viral protein encoded by the NP gene in influenza A RNA.1 It is composed of an RNA-binding domain, oligomerization domains, and polymerase binding domains, and contains two nuclear localization signals and a cytoplasmic accumulation signal, which interacts with host actin.2,3 Influenza A nucleoprotein packages the viral RNA into a helical ribonucleoprotein (RNP) complex that is a template for viral replication. Influenza A is a causative agent of seasonal flu, an acute upper respiratory infection characterized by many symptoms, including fever, dry cough, sore throat, body aches, and a runny nose and can lead to life-threatening complications in individuals with high-risk medical conditions.4 Cayman’s Influenza A Nucleoprotein Monoclonal Antibody (Clone 7B4G10G8) can be used for ELISA and Western blot (WB) applications. This recombinant antibody recognizes nucleoprotein at 53-56 kDa from H1N1 and H7N9.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gorman, O.T., Bean, W.J., Kawaoka, Y., et al. Evolution of influenza A virus nucleoprotein genes: Implications for the origins of H1N1 human and classical swine viruses. J. Virol. 65(7), 3704-3714 (1991).

    2. Portela, A., and Digard, P. The influenza virus nucleoprotein: A multifunctional RNA-binding protein pivotal to virus replication. J. Gen. Virol. 83(Pt. 4), 723-734 (2002).

    3. Digard, P., Elton, D., Bishop, K., et al. Modulation of nuclear localization of the influenza virus nucleoprotein through interaction with actin filaments. J. Virol. 73(3), 2222-2231 (1999).

    4. Moghadami, M. A narrative review of influenza: A seasonal and pandemic disease. Iran J. Med. Sci. 42(1), 2-13 (2017).