An internal standard for the quantification of L-carnitine
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Unlabeled Version(s)
21489L-Carnitine
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L-Carnitine-d9 (chloride)

Item No. 37029

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-1-propanaminium, monochloride
CAS Number
2687961-04-0
Synonyms
  • (–)-Carnitine-d9
  • Levocarnitine-d9
  • R-Carnitine-d9
Molecular Formula
C7H7D9NO3 • Cl
Formula Weight
206.7
Purity
≥99% deuterated forms (d1-d9)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMSO: 20 mg/mlEthanol: 25 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
[2H]C([2H])([N+](C([2H])([2H])[2H])(C[C@@H](CC(O)=O)O)C([2H])([2H])[2H])[2H].[Cl-]
InChi Code
InChI=1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1/i1D3,2D3,3D3;
InChi Key
JXXCENBLGFBQJM-YYKKVQPVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    5 mg

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    10 mg

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    25 mg

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    Product Description

    L-Carnitine-d9 is intended for use as an internal standard for the quantification of L-carnitine (Item No. 21489) by GC- or LC-MS. L-Carnitine is a conditionally essential nutrient.1 It is obtained from dietary sources or through the metabolism of lysine and methionine.2,3 L-Carnitine facilitates the transport of long-chain fatty acids into the mitochondrial matrix for β-oxidation, has other diverse roles on metabolism, and is involved in the maintenance of coenzyme A (CoA; Item No. 16147) stores. Plasma and/or tissue levels of L-carnitine are decreased in primary L-carnitine deficiency, a disorder characterized by impaired fatty acid oxidation, with symptoms varying depending on whether it is systemic or muscle-specific.1 Serum and tissue levels of L-carnitine are also reduced in secondary L-carnitine deficiencies caused by a variety of hereditary defects or acquired disorders.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Seim, H., Eichler, K., and Kleber, H.-P. L(–)-Carnitine and its precursor, γ-butyrobetaine. Nutraceuticals in health and disease prevention 217-256 (2001).

    2. Vaz, F.M., and Wanders, R.J.A. Carnitine biosynthesis in mammals. Biochem. J. 361(Pt 3), 417-429 (2002).

    3. Fu, L., Huang, M., and Chen, S. Primary carnitine deficiency and cardiomyopathy. Korean. Circ. J. 43(12), 785-792 (2013).