An acylcarnitine
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Isobutyryl-L-carnitine (chloride)

Item No. 37103

Technical Information
Formal Name
(2R)-3-carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxopropoxy)-1-propanaminium, monochloride
CAS Number
6920-31-6
Synonyms
  • CAR 4:0
  • C4:0 Carnitine
  • L-Carnitine isobutyryl ester
  • L-Isobutyrylcarnitine
  • ST 284
Molecular Formula
C11H22NO4 • Cl
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 25 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC(C[C@@H](OC(C(C)C)=O)C[N+](C)(C)C)=O.[Cl-]
InChi Code
InChI=1S/C11H21NO4.ClH/c1-8(2)11(15)16-9(6-10(13)14)7-12(3,4)5;/h8-9H,6-7H2,1-5H3;1H/t9-;/m1./s1
InChi Key
FWUACOYFRJEMMP-SBSPUUFOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Isobutyryl-L-carnitine is a natural 4-carbon acylcarnitine that is involved in fatty acid oxidation and organic acid metabolism.1 Elevated levels of isobutyryl-L-carnitine are associated with isobutyryl-CoA dehydrogenase deficiency.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Turer, A.T., Stevens, R.D., Bain, J.R., et alMetabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion. Circulation 119(13), 1736-1746 (2009).

    2. Koeberl, D.D., Young, S.P., Gregersen, N., et alRare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening. Pediatr. Res. 54(2), 219-223 (2003).

    3. Rinaldo, P., Cowan, T.M., and Matern, D. Acylcarnitine profile analysis. Genet. Med. 10(2), 151-156 (2008).