A multi-tail ionizable cationic phospholipid
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9A1P9

Item No. 37276

Technical Information
Formal Name
2-(dioctylamino)ethyl nonyl hydrogen phosphate
CAS Number
2760467-57-8
Molecular Formula
C27H58NO4P
Formula Weight
Purity
≥95%
A 10 mg/ml solution in ethanol
DMF: 2 mg/mlEthanol: 5 mg/ml
SMILES
O=P(OCCN(CCCCCCCC)CCCCCCCC)(OCCCCCCCCC)O
InChi Code
InChI=1S/C27H58NO4P/c1-4-7-10-13-16-19-22-26-31-33(29,30)32-27-25-28(23-20-17-14-11-8-5-2)24-21-18-15-12-9-6-3/h4-27H2,1-3H3,(H,29,30)
InChi Key
CSATVJSROKNRKV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    9A1P9 is a multi-tail ionizable cationic phospholipid.1 It induces membrane destabilization and has been used for organ-selective mRNA delivery to the spleen and liver and CRISPR-Cas9 gene editing in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, S., Cheng, Q., Wei, T., et alMembrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing. Nat. Mater. 20(5), 701-710 (2021).