A RecA inhibitor
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BRITE338733

Item No. 37302

Technical Information
Formal Name
2-[4-(5-ethyl-2-furanyl)-6-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]-2-pyridinyl]-4-methyl-phenol
CAS Number
503105-88-2
Molecular Formula
C27H35N3O2
Formula Weight
Purity
≥95%
Formulation
A solid
DMF: 1 mg/mlDMSO: 3 mg/mlEthanol: 1 mg/ml
λmax
211, 290 nm
SMILES
OC1=CC=C(C)C=C1C2=NC(NC3CC(C)(C)NC(C)(C3)C)=CC(C4=CC=C(CC)O4)=C2
InChi Code
InChI=1S/C27H35N3O2/c1-7-20-9-11-24(32-20)18-13-22(21-12-17(2)8-10-23(21)31)29-25(14-18)28-19-15-26(3,4)30-27(5,6)16-19/h8-14,19,30-31H,7,15-16H2,1-6H3,(H,28,29)
InChi Key
PKYYVDCUXJXUPN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    BRITE338733 is an inhibitor of E. coli recombinase A (RecA; IC50 = 4.7 µM for ATP hydrolysis in a cell-free assay), an enzyme involved in DNA repair.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sexton, J.Z., Wigle, T.J., He, Q., et alNovel inhibitors of E. coli RecA ATPase activity. Curr. Chem. Genomics 4, 34-42 (2010).