A synthetic bioluminescent luciferin
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Diphenylterazine

Item No. 37334

Technical Information
Formal Name
6,8-diphenyl-2-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one
CAS Number
344940-63-2
Synonyms
  • DTZ
Molecular Formula
C25H19N3O
Formula Weight
Purity
≥90%
Emission
502 nm
A solid
DMF: 11 mg/mlDMSO: 2 mg/mlEthanol: Slightly solublePBS (pH 7.2): 0.3 mg/ml
λmax
259, 450 nm
SMILES
O=C1C(CC2=CC=CC=C2)=NC3=C(C4=CC=CC=C4)NC(C5=CC=CC=C5)=CN13
InChi Code
InChI=1S/C25H19N3O/c29-25-21(16-18-10-4-1-5-11-18)27-24-23(20-14-8-3-9-15-20)26-22(17-28(24)25)19-12-6-2-7-13-19/h1-15,17,26H,16H2
InChi Key
HYQVAZNNCBIZSK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Diphenylterazine is a synthetic bioluminescent luciferin that displays an emission maximum of 502 nm.1 It has been used to quantify extracellular hydrogen peroxide when coupled to a boronated ester cage.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yeh, H.-W., Karmach, O., Ji, A., et alRed-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging. Nat. Methods 14(10), 971-974 (2017).

    2. O'Sullivan, J.J., and Heffrin, M.C. Development of an ATP-independent bioluminescent probe for detection of extracellular hydrogen peroxide. Org. Biomol. Chem. 20(31), 6231-6238 (2022).