A TRPV1 antagonist
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

SB-452533

Item No. 37379

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-bromophenyl)-N′-[2-[ethyl(3-methylphenyl)amino]ethyl]-urea
CAS Number
459429-39-1
Molecular Formula
C18H22BrN3O
Formula Weight
376.3
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
λmax
252 nm
SMILES
O=C(NCCN(CC)C1=CC=CC(C)=C1)NC2=C(Br)C=CC=C2
InChi Code
InChI=1S/C18H22BrN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23)
InChi Key
IFJYEGJUQIBBQV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $79

    Add

    10 mg

    $140

    Add

    25 mg

    $329

    Add

    50 mg

    $621

    Add
    Product Description

    SB-452533 is a transient receptor potential vanilloid 1 (TRPV1) antagonist.1 It inhibits heat-induced activation of TRPV1 in HEK293 cells expressing the human channel when used at a concentration of 1 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rami, H.K., Thompson, M., Wyman, P., et al. Discovery of small molecule antagonists of TRPV1. Bioorg. Med. Chem. Lett. 14(14), 3631-3634 (2004).