A cephalosporin antibiotic
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Cefpirome (sulfate)

Item No. 37398

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5H-cyclopenta[b]pyridinium, monosulfate
CAS Number
98753-19-6
Synonyms
  • HR 810
Molecular Formula
C22H23N6O5S2 • HSO4
Formula Weight
612.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
272 nm
SMILES
O=S(O)([O-])=O.CO/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@](SCC(C[N+]3=C4C(CCC4)=CC=C3)=C5C(O)=O)([H])N5C2=O)=O
InChi Code
InChI=1S/C22H22N6O5S2.H2O4S/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27;1-5(2,3)4/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32);(H2,1,2,3,4)/b26-15-;/t16-,20-;/m1./s1
InChi Key
RKTNPKZEPLCLSF-QHBKFCFHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cefpirome is a cephalosporin antibiotic.1 It is active against clinical isolates of various bacteria, including K. pneumoniae, E. aerogenes, Salmonella, and Shigella (MIC50s = 0.06, 0.12, 0.06, and 0.06 µg/ml, respectively). Cefpirome protects non-leukopenic mice from systemic bacterial infections induced by E. coli, S. aureus, or S. marcescens (ED50s = 0.76, 1.1, and 7.5 mg/kg, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chin, N.-X., Gu, J.-W., Fang, W., et al. In vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. Diagn. Microbiol. Infect. Dis. 15(4), 331-337 (1992).

    2. Arai, S., Kobayashi, S., and Hayashi, S. Therapeutic effects of cefpirome, a new cephalosporin, on various models of infections in mice and rats. Jpn. J. Antibiot. 43(1), (1990).